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Collagen is the most abundant protein in the body and the primary building block of your skin, muscles, bones, tendons, ligaments, and other connective tissues. It can also be found in blood vessels, organs, and intestinal lining. The main amino acids that compose collagen are proline, glycine, and hydroxyproline, which are in a triple-helix structure. Other vitamins and minerals needed to build this triple helix structure include vitamin C, zinc, and copper.

Collagen plays a significant role in providing structure, strength, and elasticity to skin and maintaining connective tissue health throughout the body. 

As the most abundant protein family, collagens—now known to include over  20 distinct types—are fundamental to the body’s structural integrity. They form the essential networks and membranes that support and connect tissues throughout the extracellular matrix. There are different types of collagen; however, type I collagen makes up 90% of your body’s collagen, which gives structure to your skin, bones, tendons, and ligaments. 

There are five main types of collagen: 

  • Type I – The most abundant, making up about 90% of the body's collagen. It forms densely packed fibers that provide structure to skin, bones, tendons, and ligaments.
  • Type II – Found in elastic cartilage, this type supports joint health and flexibility. Type III – In muscles, arteries, and internal organs, it helps maintain the structure and function of soft tissues.
  • Type IV—Located in the skin’s deeper layers, it plays a key role in filtration and forms the foundation of basement membranes.
  • Type V – Found in the cornea, hair, placenta, and some skin layers, it contributes to the structure and strength of specialized tissues. 4. What are Collagen peptides, and why are they popular for oral supplementation in the market?

Collagen peptides are a hydrolyzed form of collagen, broken down into small, easily digestible fragments for better absorption. Derived from animal or marine sources, they support the body’s natural collagen production and may help improve skin health, reduce joint pain, and promote overall connective tissue function

These are primarily type I premium marine collagen peptides with a low molecular weight of 2000 Da, sourced from Europe, and clinically proven for their effects.*

Many studies show collagen sourced from marine organisms, such as fish, is highly advantageous over other sources as they are metabolically compatible, lack religious constraints, and are free of animal pathogens or hormones.

In contrast, land animals may possess many transmissible diseases, which make them less favorable. Additionally, many studies show the benefits of marine collagen in terms of its potential to increase wound healing rates and anti-aging properties.

Collagen synthesis begins to decline in the mid-twenties, at a rate of approximately 1.5% per year. The first signs of aging, such as wrinkles, generally become noticeable in the 30s. As the body’s ability to regenerate slows, skin hydration and elasticity decrease, which is a natural consequence of aging.

With the decline in collagen production, skin becomes thinner and less resilient, and the body’s connective tissues, such as tendons, lose flexibility, contributing to stiffness and discomfort over time.

Environmental factors, including ultraviolet sunlight, smoking, and a diet high in sugar and refined carbohydrates (which increase the risk of advanced glycation end products), can damage collagen by reducing its strength and thickness. Collagen damage or loss can lead to early signs of skin aging, such as fine lines, wrinkles, dryness, and sagging. Starting in their mid-20s, individuals—particularly those exposed to stress, toxins, and UV rays—may benefit from supplementing with balanced nutrients or premium collagen to help counteract the natural decline in collagen production.

Limitations and Considerations

Research shows promising benefits of marine collagen and fruit extracts for skin, joints, and overall health. Some studies are funded by the supplement industry, so choosing products tested by third parties ensures quality and safety. Ongoing research will continue to clarify their full potential.

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